J Korean Neurol Assoc.  1983 Dec;1(2):21-30.

A Study on Tuberculous Meningitis in Adults: With special reference to abnormal neurologic sings and prognosis

• Roh JK

Abstract

Author reviewed clinical and labaratory findings in seventy-five adult patients of tuberculous meningitis aged from 15 to 73 years with special reference to abnormal neurologic signs and prognostic factors of their outcome. Majority of their diagnosis were made by presumptive basis except six cases of AFB positive in CSF. They were classified into 3 stages by clinical criterions at admission. Five (6.7% ) of them died, and seven patients (9.3%) discharged with aggravated results; twelve (16%) of them improved with some sequelae at discharge, and fifty-one (68%) improved without sequelae. These outcomes correlated well with their clinical stages at admission. Observed abnormal neurologic findings and their percentages were as followings; meningeal irritation sign (69%), SIADH (16%), ocular paresis (25%), papilledema (12%), visual loss (5%), hemiparesis (13%), radiculomyelopathy (9%), seizure (9%), cerebellar dysfunction (7%), and peripheral type of facial palsy (3%). CSF findings at admission and during illness were examined also, but they had a little correlation with the clinical course. Accompanied tuberculous infections of other organs were discovered in forty cases (53%) of the patients.

MeSH Terms

Adult*
Cerebellar Diseases
Diagnosis
Facial Paralysis
Humans
Inappropriate ADH Syndrome
Neurologic Manifestations
Papilledema
Paresis
Prognosis*
Seizures
Tuberculosis, Meningeal*