J Korean Ophthalmol Soc.  1978 Sep;19(3):303-307.

Angioid Streaks of the Retina Associated with Pseudoxanthoma Elasticum

• Kwon JS
• Kim HB
• Choi O

Abstract

Angioid streaks are a peculiar spoke-like distribution of dark-colored broad lines in the retinaradiating out from the optic nerve in a fashion similiar to the branching of blood vessels. It is thought to be due to breaks in the elastic lamina of Bruch's membrane. Their colour may be reddish-brown. dark-brown, grey or even in parts white. During a ophthalmoscopic examination they may be mistaken for retinal vessels. The lesion, however, lies beneath the retinal and above the choroidal vessels. Angioid streaks are most commonly seen in pseudoxanthoma elasticum, Paget's disease of bone and sickle cell anemia. Angioid streaks with pseudoxanthoma elasticum have been reported in all races and in all decades of life. The peak age lies between 30 and 50. Pseudoxnnthoma elasticum is a dermatologic condition characterized by changes in the elastic tissue of the skin. A 21 year old Korean lady with pseudoxanthoma e!asticum has been found to have angioid streaks in her both fundi.

MeSH Terms

Anemia, Sickle Cell
Angioid Streaks*
Blood Vessels
Bruch Membrane
Choroid
Continental Population Groups
Elastic Tissue
Humans
Optic Nerve
Osteitis Deformans
Pseudoxanthoma Elasticum*
Retina*
Retinal Vessels
Retinaldehyde
Skin
Young Adult
Retinaldehyde