J Korean Soc Ther Radiol.  1988 Jun;6(1):13-22.

Radiotherapy Results of Nasopharyngeal Carcinoma

• Lee JY
• Loh JJ
• Suh CO
• Lee YG
• Hong WP

Abstract

This study is the retrospective evaluation of ninety-six patients with biopsy-proven carcinoma of nasopharynx treated with radiotherapy at Yonsei University, College of Medicine, radiation Oncology from January 1971 to December 1985. Patient's age ranged from 15 to 71 years with a median age of 49 years. Fifty-two point five percent of local control and 47.5% of actuarial 5 year survival were achieved with radical radiotherapy. Five year survival rate for Stage I & II, III and IV were 75.0%, 74.6% and 41.4%, respectively. Distant metastasis rate was related with N stage (N1 12.5%, N1 0%, N2 23.5%, N3 32.1%) and histologic type (lymphoepithelioma 41.7%, squamous cell carcinoma 6.5%) but not with T stage. Thirty-one of sixty-seven patient covered adequate radiation field received induction chemotherapy. However induction chemotherapy dose not appear to improve over all survival.

Keyword

Nasophargngeal carcinoma; Radiotherapy; Survival

MeSH Terms

Carcinoma, Squamous Cell
Humans
Induction Chemotherapy
Nasopharynx
Neoplasm Metastasis
Radiation Oncology
Radiotherapy*
Retrospective Studies
Survival Rate