J Korean Soc Ther Radiol.  1987 Jun;5(1):37-42.

Angiofollicular Lymph Node Hyperplasia(=Castleman's Disease): Report of A Case

• Gil HJ
• Oh YK
• Yoon SC
• Shinn KS
• Bahk YW

Abstract

Angiofollicular lymph node hyperplasia (AFLNH) with well marginated lymphoid masses, is a rare benign disease of unknown etiology. The majority of the disease develop intrathoracically. Histologically this disease can be divided into the hyaline-vascular and the plasma cell types with the hyaline-vascular type prevailing. The plasma cell variant has been associated with nephritic syndrome, anemia, growth failure, fever, hyperglobulinemia, peripheral neuropathy, and hypoalbuminemia. Surgical resection is known to be treatment of choice in most cases, and radiotherapy is reserved for advanced, unresectable lesions. We report a complete remission of AFLNH in a case treated by surgical excision followed by irradiation.

Keyword

Angiofollicular lymph node hyperplasia; Hyaline-vascular type; Plasma cell type; radiotherapy

MeSH Terms

Anemia
Fever
Giant Lymph Node Hyperplasia
Hypoalbuminemia
Lymph Nodes*
Peripheral Nervous System Diseases
Plasma Cells
Radiotherapy