J Korean Soc Ther Radiol.  1986 Jun;4(1):55-62.

The treatment Results of Radiotherapy for nonsmall Cell Lung Cancer

• Yoon JC

Abstract

From Nov. 1983 through Jan. 1986, 43 patients with nonsmall cell lung cancer were treated by radiation therapy at Inje Medical College Paik Hospital. 38 patients were available for the analysis of this study. 33 patients received definite irradiation with curative intent, while 5 patients received postoperative irradion. Chemotherapy was added in 12 patients before, during and after radio-therapy. 28 patients were squamous cell carcinoma and 10 patients were adenocarcinoma. There were 29 men and 9 women (median age, 58 years; range 34 to 74 years). Stage 1 was 1 patients, Stage 11, 7 patient, and Stage 111, 30 patients. Among 33 patients who received radiotherapy with curative intent, follow up radiological study revealed complete response in 12 patients (36%), partial response, in 9 patients (27%), and minimal response, in 5 patients (15%), while 7 patients (21%) were nonresponders. Median survival for all patients was 6.9 months; squamous cell carcinoma, 7.3 months, adenocarcinoma, 5.9 months. Responders survived median 7 months, while nonresponders survived median 1.9 months. Improved complete response rate and survival were shown in high radiation dose group. As prognostic factors, age, initial performance status, sex, histology and tumor location were evaluated.

Keyword

Nonsmal cell lung cancer; Radiotherapy; Response; Survival Prognostic factors

MeSH Terms

Adenocarcinoma
Age Factors
Carcinoma, Non-Small-Cell Lung*
Carcinoma, Squamous Cell
Drug Therapy
Female
Follow-Up Studies
Humans
Male
Radiotherapy*