Tuberc Respir Dis.  2004 Sep;57(3):289-291. 10.4046/trd.2004.57.3.289.

Massive Pleural Effusion as the First Manifestation of Malignant Melanoma Metastasis

Affiliations
  • 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. Jaehwa.Cho@inha.ac.kr
  • 2Department of Pathology, Inha University College of Medicine, Incheon, Korea.

Abstract

Malignant melanoma develops from melanocytes and frequently metastases to other organs. Common metastatic sites are other skin, lymph nodes, lung, liver, brain and bone in decreasing order of frequency. Malignant pleural effusion is less frequent manifestation of thoracic metastasis. We experienced a 57-year-old man with pleural effusion who received radical resection with local flap on left foot due to acral lentiginous melanoma 3 years ago. He had progressive chest pain and left massive pleural effusion. The pleural cytology and biopsy showed malignant melanoma. After closed thoracostomy and talc pleurodesis, he refused further immunotherapy and chemotherapy and discharged.

Keyword

Malignant melanoma; Pleural effusion

MeSH Terms

Biopsy
Brain
Chest Pain
Drug Therapy
Foot
Humans
Immunotherapy
Liver
Lung
Lymph Nodes
Melanocytes
Melanoma*
Middle Aged
Neoplasm Metastasis*
Pleural Effusion*
Pleural Effusion, Malignant
Pleurodesis
Skin
Talc
Thoracostomy
Talc
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