J Korean Soc Neonatol.  2002 May;9(1):57-64.

Linear and Non-linear Analysis of Cardiovascular System in Preterm Infants

• Park EY
• Yum MK
• Moon SJ

Abstract

PURPOSE: We investigated the autonomic and complex modulation in heart rate and blood pressure in preterm infants.
METHODS
In 20 healthy preterm infants and 20 full-term infants (gestational age of 32.5+/-2.3 and 39.2+/-1.0 weeks each, P<0.0001), we recorded electrocardio gram and non-invasive blood pressure simultaneously and continuously during their sleep in the supine position. To evaluate the autonomic and complex modulation in heart rate and blood pressure, we performed power spectral analysis and analysis of the determinism.
RESULTS
When compared to full-term infants and in the analysis of R-R interval, the preterm infants had significantly lower high-frequency power (30.7+/-15.1% vs 20.3+/-7.7%, P<0.05), higher low- to high-frequency power ratio (1.9+/-1.6 vs 3.0+/-2.1, P<0.05), and significantly lower prediction error (4.1+/-2.8% vs 2.9+/-1.3%, P<0.05). In the analysis of blood pressure, they showed no significant difference.
CONCLUSION
Compared to heart rates of full-term infants, the heart rates of preterm infants are less modulated by cardiac parasympathetic activity and more deterministic.

Keyword

Preterm infants; Heart rate; Blood pressure; Spectral analysis; Determinism

MeSH Terms

Blood Pressure
Cardiovascular System*
Heart Rate
Humans
Infant
Infant, Newborn
Infant, Premature*
Supine Position