J Korean Epilepsy Soc.  2004 Dec;8(2):163-166.

A Case of Idiopathic Localized Hypertrophic Pachymeningitis Presented with Partial Seizures

Affiliations
  • 1Department of Neurology, College of Medicine, Ewha Womans University and Ewha Medical Research Institute, Seoul, Korea. leeh@ewha.ac.kr
  • 2Department of Neurosurgery, College of Medicine, Ewha Womans University and Ewha Medical Research Institute, Seoul, Korea.
  • 3Department of Pathology, College of Medicine, Ewha Womans University and Ewha Medical Research Institute, Seoul, Korea.

Abstract

Idiopathic hypertrophic pachymeningitis is a clinical disorder caused by a localized or diffuse thickening of the dura mater, with an associated chronic inflammation. This can be diagnosed when there is no evidence of other etiologies such as trauma, infection, tumors, and Wegener's disease. Clinical manifestations are chronic headache with or without neurological manifestations such as cranial nerve palsies, cerebellar ataxia, neuro-ophthalmologic complications, and rarely clinical seizures. We described a patient with simple partial seizures with focal sensory and motor symptoms in the right hand as an initial and the only clinical manifestation, accompanied by a tumor-like lesion in the left parietal convexity on brain MRI. The patient underwent a lesionectomy, and the seizures have been well controlled so far without immunosuppressant treatment.

Keyword

Idiopathic hypertrophic pachymeningitis; Partial seizures; Lesionectomy

MeSH Terms

Brain
Cerebellar Ataxia
Cranial Nerve Diseases
Dura Mater
Epilepsies, Partial
Hand
Headache Disorders
Humans
Inflammation
Magnetic Resonance Imaging
Meningitis*
Neurologic Manifestations
Rabeprazole
Seizures*
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