J Korean Neurol Assoc.
2005 Jun;23(3):402-404.
A Case of Isolated Aspergillus Sphenoid Sinusitis
- Affiliations
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- 1Department of Neurology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea. circo@lycos.co.kr
- 2Department of Otolaryngology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.
- 3Department of Radiology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea.
Abstract
- Isolated Aspergillus infection originating within the sphenoid sinus is most often associated with the immunocompromised patient. A 53-year-old healthy woman presented with a 3-week history of headache and subsequent left 6th nerve palsy. Brain MRI demonstrated a space-occupying lesion within sphenoid sinus. Histological analysis through transnasal-transsphenoidal approach revealed numerous Aspergillus hyphae. Postoperatively, all symptoms resolved completely without anti-fungal treatment. Isolated Aspergillus sphenoid sinusitis should be routinely included in the differential diagnosis of patients with acute or subacute headache, even in nonimmunosuppressed patients.
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