Korean J Dermatol.
2004 Dec;42(12):1603-1605.
A Case of Palisaded Encapsulated Neuroma of the Eyelid
- Affiliations
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- 1Department of Dermatology, Yonsei University College of Medicine, Korea. dbang@yumc.yonsei.ac.kr
- 2Department of Dermatology, Ajou University College of Medicine, Seoul, Korea.
Abstract
- Palisaded encapsulated neuroma (PEN) is a rare intraneural neuroma. It usually occurs as a solitary asymptomatic skin-colored papule, and commonly affects the butterfly area of the face of middle-aged adults. We report a case of PEN which developed on the right upper eyelid of a 30-year-old man. It was a 3 mm-sized skin colored papule, and histologically, there was a well- defined encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading pattern. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was positive for epithelial membrane antigen.
