Korean J Dermatol.  2002 Apr;40(4):445-448.

A Case of Epidermolytic Palmoplantar Keratoderma

• Kang SK
• Roh KH
• Chang SE
• Choi JH
• Sung KJ
• Moon KC
• Koh JK

Abstract

Palmoplantar keratodermas are divided into autosomal dominant and autosomal recessive groups by the mode of transmission. The autosomal dominantly transmitted group is further divided into epidermolytic and nonepidermolytic types according to the histological findings. Hereditary epidermolytic palmoplantar keratoderma manifests clinically as a localized thickening of the palms and soles. Herein we report a 29-year-old woman showing the typical clinical and histologic features of epidermolytic palmoplantar keratoderma without family history. This case could be spontaneous mutations that will later breed a true autosomal dominant trait.

Keyword

Epidermolytic palmoplantar keratoderma; Spontaneous mutation

MeSH Terms

Adult
Female
Humans
Keratoderma, Palmoplantar
Keratoderma, Palmoplantar, Epidermolytic*