Korean J Dermatol.
2001 Mar;39(3):354-357.
A Case of lupus vulgaris diagnosed with polymerase chain reaction
- Affiliations
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- 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. derm@www.amc.seoul.kr
Abstract
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Lupus vulgaris is the most common form of cutaneous tuberculosis showing various clinical manifestations. Because AFB staining and culture are often negative, diagnosis can be difficult. Polymerase chain reaction with high sensitivity and specificity may improve the diagnostic panel for cutaneous tuberculosis. We report a case of lupus vulgaris in a 5 year-old girl. The presence of Mycobaterium tuberculosis DNA in a skin biopsy demonstrated by polymerase chain reaction led to the diagnosis of lupus vulgaris.