J Korean Rheum Assoc.
2001 Mar;8(1):48-52.
A Case of Protein-Losing Enteropathy Associated with Systemic Lupus Erythematosus
- Affiliations
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- 1The Hospital For Rheumatic Diseases, Hanyang University Medical College. Seoul, Korea. thkim@hanyang.ac.kr
- 2Department of Pathology, Hanyang University Medical College.
Abstract
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Systemic lupus erythematosus (SLE) is a multisystemic disease that can affect most organ system, although gastrointestinal (GI) manifestations are relatively uncommon. Protein losing enteropathy (PLE) is associated with several clinical disorders, but it is an unusual manifestation of SLE. Of over 20 reported cases of PLE associated with SLE, the pathogenesis of lupus associated PLE remains unclear. We describe a patient with edema, diarrhea, abdomianl pain, and hypoalbuminemia who had been diagnosed SLE. PLE was diagnosed by the method of alpha1-antitrypsin clearance in stool.