J Korean Rheum Assoc.
2005 Jun;12(2):116-120.
Intravascular Histiocytosis in a Patient with Rheumatoid Arthritis
- Affiliations
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- 1Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ysong@snu.ac.kr
- 2Departments of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- Intravascular histiocytosis is an unusual cutaneous lesion with massive aggregates mainly composed of histiocytes in markedly dilated dermal vessel and previously reported in associations with rheumatoid arthritis (RA). We report a case of intravascular histiocytosis in RA patient. A 58-year-old woman having 20-year history of RA presented with the right elbow pain and poorly demarcated, indurated erythema in the right forearm. Biopsy revealed vascular proliferation and mononuclear cellular aggregates in the dilated vessels of dermis. Immunohistochemical findings of the intravascular cells were consistent with a histiocytic differentiation. She underwent synovectomy in the right elbow joint and had rapid resolution of cutaneous lesion.
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