Korean J Gastroenterol.  2000 Feb;35(2):247-252.

A Case of Guillain-Barr Syndrome with 6th Cranial Nerve Palsy Complicated by Chronic Active Hepatitis B

• Seo MW
• Ahn DS
• Lee CS
• Lee ST
• Lee SO
• Lee HB
• Kim DG

Abstract

Viral hepatitis may injure the central and peripheral nervous system, resulting in encephalitis, meningitis, myelitis, isolated pyramidal or extrapyramidal tract dysfunction, seizures, mononeuritis, plexitis, and psychiatric disturbances. Hepatitis associated Guillain-Barr syndrome mostly occurs as a complication of acute hepatitis, but is caused rarely by chronic active hepatitis B. Usually, Guillain-Barr syndrome is associated with peripheral nervous dysfunction and rarely involve central nervous system. However, Guillain-Barr syndrome with the 6th cranial nerve palsy resulted from chronic active hepatitis B is extremly rare. Recently, we experienced the case of Guillain-Barr syndrome with the 6th cranial nerve palsy in 21-year-old man with chronic active hepatitis B. He was improved with interferon-alpha2b and ordinary conservative treatment. Here, we report a rare clinical case of Guillain- Barr syndrome with the 6th cranial nerve palsy complicated by chronic active hepatitis B with a review of literatures.

Keyword

Guillain-Barr syndrome; Chronic active hepatitis B; Cranial nerve palsy

MeSH Terms

Central Nervous System
Cranial Nerve Diseases*
Cranial Nerves*
Encephalitis
Extrapyramidal Tracts
Hepatitis
Hepatitis, Chronic*
Humans
Meningitis
Mononeuropathies
Myelitis
Peripheral Nervous System
Seizures
Young Adult