Korean J Lab Med.
2002 Aug;22(4):220-223.
A Case of Acute Lymphoblastic Leukemia with dic(9;12) and Additional Trisomy 8
- Affiliations
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- 1Department of Laboratory Medicine,Chonnam National University Medical School, Gwangju, Korea. ryang@hitel.net
- 2Department of internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
- 3Research Institute of Medical Sciences, Chonnam National University Medical School, Gwangju, Korea.
Abstract
- A 16-year-old boy was diagnosed with acute lymphoblastic leukemia with dic(9;12). Physical examination revealed cervical lymphadenopathy and splenomegaly. Hemoglobin was 5.1 g/dL, WBC was 4,400/microL and the platelet count was 3,000/ L. Immunophenotyping showed positivity of HLA-DR, CD34, CD10, CD19, CD20, and CD22. The chromosome analysis of bone marrow aspirate showed 46,XY,+8,dic(9;12)(p11-13;p11-12). There has been a complete remission by induction chemotherapy as of the 62nd day.
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