Korean J Infect Dis.  1997 Sep;29(5):413-416.

The Results of Antimalarial Treatment of Resurgent Vivax Malaria in Korea

Affiliations
  • 1Departments of Clinical Pathology, College of Medicine, Korea University, Seoul, Korea.
  • 2Departments of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
  • 3Department of Parasitology, College of Medicine, Inje University, Pusan.
  • 4Departments of Public Health, College of Medicine Hallym University, Seoul, Korea.
  • 5Departments of Preventive Medicine, College of Medicine Hallym University, Seoul, Korea. lim1163@chollian.net

Abstract

BACKGROUND: We evaluated the posttreatment response to chloroquine among 81 patients with vivax malaria who were residents in Northern area of Kyunggi province in 1996. The result of chloroquine therapy was followed 28 days after treatment. Material and
METHODS
Diagnosis of malaria was made by microscopic examination of Giemsa stain of peripheral blood. Parasitemia levels from each patient were counted before treatment, 3, 14 and 28 days after treatment.
RESULTS
Eight-one patients successfully completed the therapy. All patients were army soldiers, who were residing in northern area of Kyunggi province. The 14-day cumulative incidence of therapeutic failure for P. vivax was 2.5% (n=2) and 0% (n=81) at 28th day. One patient had a recurrence eight months after completion of antimalarial treatment.
CONCLUSION
The results suggest that recent resurgent malaria in Korea need more careful therapy. Antimalarial treatment should not be completed without microscopic confirmation.

Keyword

Plasmodium vivax; Korea; Treatment; Chloroquine; Primaquine

MeSH Terms

Azure Stains
Chloroquine
Diagnosis
Gyeonggi-do
Humans
Incidence
Korea*
Malaria
Malaria, Vivax*
Military Personnel
Parasitemia
Plasmodium vivax
Primaquine
Recurrence
Azure Stains
Chloroquine
Primaquine
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