Korean J Biol Psychiatry.
2006 Aug;13(3):178-190.
Relationship between Alcohol Withdrawal Symptoms and Dopaminergic Gene Polymorphisms(DRD2, DAT, COMT) in Alcohol Dependence Patients
- Affiliations
-
- 1Department of Neuropsychiatry, Chung-Ang University School of Medicine, Seoul, Korea. hawkeyelys@hanmail.net
- 2Department of Neuropsychiatry, Seoul University School of Medicine, Seoul, Korea.
Abstract
- with DAT-9 gene allele. And The total score of CIWA-Ar scale in the subject without DAT-9 gene allele was significantly higher than in the subject with DAT-9 gene allele. COMT: The total score of CIWA-Ar scale in heterozygote was significantly higher than in homozygote.
CONCLUSION
Our results suggest the relationship between specific genetic factors and the withdrawal symptoms of alcohol dependent patients. As the candidate gene of the severity of alcohol withdrawal syndrome, DRD2 Taq1 gene was recommended.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The Effect of ADH1B and NQO2 Polymorphisms on the Age of Onset of Alcohol Dependence and Alcohol Withdrawal Symptoms
- Alcohol Withdrawal and Serum Nitrite Concentration
- Association between D2 Dopamine Receptor Gene Polymorphisms and Reward Dependence Personality Traits
- Association Study of Dopamine Transporter(DATI) G2319A Genetic Polymorphism in Alcohol Dependence
- A Study on the Types of Alcohol Dependence by Alcohol Use Inventory and Their Characteristics
