J Korean Soc Hypertens.  2013 Jun;19(2):45-54. 10.5646/jksh.2013.19.2.45.

Association of Blood Pressure and Heart Rate Response to Graded Exercise Test with Left Atrial Volume Index and Pulse Wave Velocity

Affiliations
  • 1Department of Internal Medicine, Regional Cardiovascular Center, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea. jojeong@cnu.ac.kr

Abstract

BACKGROUND
Exaggerated blood pressure (BP) response to exercise can be an independent risk factor for cardiovascular mortality and morbidity. The purpose of this study was to define the factor that effect on early systolic BP response to exercise.
METHODS
We examined echocardiographic data, BP, heart rate from graded exercise test and brachial ankle pulse wave velocity (PWV) of 205 patients (137 men and 68 women; mean age 58 +/- 11 years; range, 19 to 83 years). Graded exercise test was conducted in BRUCE protocol. We define delta systolic blood pressure (SBP) as systolic BRUCE stage "n" BP minus baseline BP.
RESULTS
Resting BP (127 +/- 16 mm Hg) was elevated to 171 +/- 26 mm Hg after peak graded exercise test. Resting heart rate (80 +/- 15 bpm) was increased to 146 +/- 27 bpm after peak graded exercise test. Stepwise regression test between baseline SBP, delta SBP, maximal SBP and left atrial volume index (LAVI) was done. Supine SBP, delta SBP, maximal SBP was not associated with LAVI (p > 0.5). But increased LAVI was significantly associated with delta SBP1 in woman (R2 = 0.192, p = 0.002). PWV was significantly associated with base line (R2 = 0.311, p < 0.01) and maximal SBP (R2 = 0.051, p < 0.01). However, PWV was not associated with delta SBP.
CONCLUSIONS
LAVI and PWV were not associated with early SBP response to exercise. But in women, elevation of early SBP during exercise is associated with LAVI.

Keyword

Exercise test; Pulse wave analysis; Blood pressure; Heart rate

MeSH Terms

Blood Pressure*
Exercise Test*
Female
Heart Rate*
Heart
Humans
Male
Pulse Wave Analysis*
Risk Factors
Mustard Compounds
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