Korean J Med Phys.  2008 Jun;19(2):125-130.

Assessment on Gastrointestinal Transit Movement of Capsule Endoscopy in Beagle Dogs

• Chang HS
• Yang HT
• Kim SY
• Woo DC
• Park WD
• Yong JH
• Choe BY
• Kim HY
• Choi CB

Abstract

The object of this study is to measure the transit time and passage rate of capsule endoscopy (CE) in the gastrointestinal tract in medium sized beagle dogs (7~13 kg). Animals were divided into four groups: only capsule (group 1, n=10), capsule+water (group 2, n=10), mettoclopramide+capsule (group 3, n=10), metoclopramide +capsule+water (group 4, n=10). The capsule transit times through the stomach and small bowel were evaluated by radiography findings. Gastric transit time (GTT), small intestinal transit time (SITT) and complete passage rate were measured in four groups. GTT's for each group were as follows; 45+/-20 min (group 1), 117+/-35 min (group 2), 150+/-40 min (group 3), and 154+/-65 min (group 4), while SITT's were 75+/-20 min (group 1), 195+/-55 min (group 2), 70+/-15 min (group 3), and 76+/-15 min (group 4). The complete passage rates were 20% (group 1), 40% (group 2), 20% (group 3), 50% (group 4). In all groups, if CE could pass through the pylorus, it passed all small intestinal tracts within 8 hours (battery life). Administration of water helped CE to pass pylori, except in case of metoclopramide administration. These results indicate that CE could be an useful tool for examining gastrointestinal diseases in the veterinary medicine.

Keyword

Capsule endoscopy; Gastric transit time; Complete passage rate; Beagle

MeSH Terms

Animals
Capsule Endoscopy
Dogs
Gastrointestinal Diseases
Gastrointestinal Tract
Gastrointestinal Transit
Metoclopramide
Pylorus
Stomach
Veterinary Medicine
Water
Metoclopramide
Water