J Korean Endocr Soc.  2008 Oct;23(5):337-341. 10.3803/jkes.2008.23.5.337.

A Case of Painful Graves' Disease

• Jeong JY
• Kim TY
• Kim EH
• Kim EY
• Lee SA
• Yim JH
• Kim KM
• Kim WB
• Shong YK

• KMID: 1479227
• DOI: http://doi.org/10.3803/jkes.2008.23.5.337

Abstract

Graves' disease rarely presents as pain and tenderness of goiter, with only a few cases reported in the literature. We describe a case of painful Graves' disease presenting as 2 episodes of painful goiter.

Keyword

Graves' disease; painful goiter; painful Hashimoto's thyroiditis

MeSH Terms

Cinnarizine
Goiter
Graves Disease
Cinnarizine

Figure

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  Fig. 1 99mTechnetium pertechnate thyroid scans shows increased uptake in both lobe and diffuse enlargement.

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  Fig. 2 Thyroid ultrasonography reveals a diffusely enlarged gland with heterogeneous echogenecity without focal abnormality. (A) Right lobe (B) Left lobe.

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  Fig. 3 Changes in symptom, signs, thyroid function, and treatment. Total T3: normal range, 98-180 ng/dL. Free T4: normal range, 0.8-1.9 ng/dL. TSH: Thyroid stimulating hormone, normal range, 0.4~5.0 µIU/mL. TBII: TSH-binding inhibitor immunoglobulin measured by BRAHMS DYNOtest® TRAK human, normal range, 0~2.0 IU/L. d: day. m: month.

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