Korean J Nephrol.  2008 Sep;27(5):631-637.

A Case of Pneumocystis jirovecii Pneumonia Following CMV Duodenitis in a Kidney Transplant Patient

• Kim HW
• Kim MG
• Woo YS
• Boo CS
• Jo SK
• Kim HK
• Jo WY
• Lee KG
• Kim HO
• Oh CR
• Kim JH

Abstract

Solid organ transplant recipients are at increased risk for various opportunistic infections because of their immunocompromised state. Pneumocystis jirovecii (carinii) infection has posed serious problems in these patients which can be life threatening. It has been reported that incidences of Pneumocystis infection have dramatically decreased with the use of prophylactic antibiotics. However, there have been reports that say the risks of Pneumocystis infection are increasing with the use of new immunosuppressive drugs and in presence of preceding immunomodulating infections such as CMV infection which is another common opportunistic infection in transplant patients. There were only a few case reports abroad on Pneumocystis infection following CMV infection in patients who underwent kidney transplantation. In Korea, however, there hasnt been any report of such cases. Herein we report a case of a kidney transplant patient who experienced a serious episode of Pneumocystis jirovecii pneumonia following CMV duodenitis. After adequate mechanical ventilation and use of antibiotics the patient completely recovered without any complications.

Keyword

Kidney transplantation; Pneumocystis; Cytomegalovirus

MeSH Terms

Anti-Bacterial Agents
Cytomegalovirus
Duodenitis
Humans
Incidence
Kidney
Kidney Transplantation
Korea
Opportunistic Infections
Pneumocystis
Pneumocystis Infections
Pneumocystis jirovecii
Pneumonia
Respiration, Artificial
Transplants
Anti-Bacterial Agents