Gut Liver.  2009 Jun;3(2):116-121. 10.5009/gnl.2009.3.2.116.

Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Diagnosis of Pancreatic and Peripancreatic Lesions: A Single Center Experience in Korea

• Hwang CY
• Lee SS
• Song TJ
• Moon SH
• Lee D
• Park DH
• Seo DW
• Lee SK
• Kim MH

• KMID: 1464754
• DOI: http://doi.org/10.5009/gnl.2009.3.2.116

Abstract

BACKGROUND/AIMS
Although endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has been introduced and its use has been increasing in Korea, there have not been many reports about its performance. The aim of this study was to assess the utility of EUS-FNA without on-site cytopathologist in establishing the diagnosis of solid pancreatic and peripancreatic masses from a single institution in Korea.
METHODS
Medical records of 139 patients who underwent EUS-FNA for pancreatic and peripancreatic solid mass in the year 2007, were retrospectively reviewed. By comparing cytopathologic diagnosis of FNA with final diagnosis, sensitivity, specificity, and accuracy were determined, and factors influencing the accuracy as well as complications were analyzed.
RESULTS
One hundred twenty out of 139 cases had final diagnosis of malignancy. Sensitivity, specificity, and accuracy of EUS-FNA were 82%, 89%, and 83%, respectively, and positive and negative predictive values were 100% and 46%, respectively. As for factors influencing the accuracy of FNA, lesion size was marginally significant (p-value 0.08) by multivariate analysis.
CONCLUSIONS
EUS-FNA performed without on-site cytopathologist was found to be accurate and safe, and thus EUS-FNA should be a part of the standard management algorithm for pancreatic and peripancreatic mass.

Keyword

EUS-FNA; Pancreatic neoplasms; Peripancreatic mass; Diagnostic accuracy

MeSH Terms

Biopsy
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Humans
Korea
Medical Records
Multivariate Analysis
Pancreatic Neoplasms
Retrospective Studies
Sensitivity and Specificity