Infect Chemother.  2010 Aug;42(4):216-222. 10.3947/ic.2010.42.4.216.

Interventions to Prevent Catheter-Associated Blood-stream Infections: A Multicenter Study in Korea

• Yoo S
• Jung SI
• Kim GS
• Lim DS
• Sohn JW
• Kim JY
• Kim JE
• Jang YS
• Jung S
• Pai H

• KMID: 1457381
• DOI: http://doi.org/10.3947/ic.2010.42.4.216

Abstract

BACKGROUND
The purpose of this study was to determine the efficacy of infection-control interventions to decrease the incidence of catheter-associated bloodstream infections (CA-BSI) and to examine the sustainability of its effect during and after the intervention in Korea.
MATERIALS AND METHODS
We conducted a prospective multi-strategy intervention in intensive care units (ICUs) at 3 university hospitals in Korea. The intervention consisted of education and on-site training for medical personnel involved in catheter care, active surveillance, and reinforcement of current intervention in each unit. After the intervention of 3 months, we identified CA-BSI cases of each hospital using the electronic database for 6 months.
RESULTS
During the intervention, the number of CA-BSI decreased significantly compared to pre-interventional period (8.7 vs. 2.3 per 1,000 catheter days; rate ratio 0.28; 95% CI, 0.13-0.61). After the intervention, CA-BSI rate increased slightly, but was still significantly lower than that of pre-interventional period (4.3 per 1,000 catheter days; rate ratio, 0.49; 95% CI, 0.31-0.78). Reduction of gram-negative bacterial infections was noted during and after the intervention.
CONCLUSIONS
A multi-strategy approach to reduce CA-BSI could be implemented in diverse settings of medical and surgical units in Korea and decreased CA-BSI rates during the intervention.

Keyword

Catheter-associated bloodstream infections; Healthcare associated infection; Intensive care unit; Intervention

MeSH Terms

Catheters
Electronics
Electrons
Gram-Negative Bacterial Infections
Hospitals, University
Incidence
Intensive Care Units
Korea
Prospective Studies
Reinforcement (Psychology)

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