Korean J Dermatol.  2010 Jan;48(1):60-64.

A Case of Platelet-rich Plasma (PRP) Treatment for Herpes Zoster Ophthalmicus-like Skin Necrosis after Filler Injection

Affiliations
  • 1Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. janylove99@dsmc.or.kr

Abstract

Dermal fillers are increasingly being used for facial soft tissue augmentation. In the appropriate patient and with appropriate training, dermal fillers can temporally eliminate facial wrinkles and depressed scars. Although complications are rare, they can occur with any dermal filler. Especially, injection necrosis is a rare, but clinically important potential complication that is caused by interruption of the vascular supply to the area by compression, injury and/or obstruction of the vessel. Injection necrosis can appear to be pyoderma or a local wound infection, and so physicians should pay attention to make an accurate diagnosis. We report here on a case of a 47-year-old female who experienced sudden onset local necrosis of the glabella area after filler injection, and this was followed by a herpes zoster ophthalmicus-like necrotic lesion. We treated the necrotic lesion on the glabella area by wound dressing combined with platelet-rich plasma (PRP) treatment.

Keyword

Filler; Necrosis; Platelet-rich plasma

MeSH Terms

Bandages
Cicatrix
Female
Glycosaminoglycans
Herpes Zoster
Humans
Middle Aged
Necrosis
Platelet-Rich Plasma
Pyoderma
Skin
Wound Infection
Glycosaminoglycans
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