Korean J Thorac Cardiovasc Surg.  2011 Oct;44(5):323-331. 10.5090/kjtcs.2011.44.5.323.

On-Pump versus Off-pump Myocardial Revascularization in Patients with Renal Insufficiency: Early and Mid-term Results

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea.
  • 2Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea. jwlee@amc.seoul.kr
  • 3Department of Thoracic and Cardiovascular Surgery, Pusan National University Yang-San Hospital, Korea.

Abstract

BACKGROUND
Myocardial revascularization in patients with renal insufficiency is challenging to the cardiac surgeon, irrespective of utilizing extracorporeal circulation. This study aimed to compare the number of bypass grafts and the mid-term results and to evaluate independent survival predictors in patients with renal insufficiency undergoing on-pump or off-pump myocardial revascularization.
MATERIALS AND METHODS
We retrospectively analyzed the data of 103 patients with renal insufficiency, who had isolated myocardial revascularization between January 1999 and January 2009. The patients were divided into two groups, the on-pump group and the off-pump group.
RESULTS
The off-pump group received a significantly greater number of distal arterial grafts than the on-pump group. However, the mean number of total grafts, the degree of complete revascularization, and survival rate of the patients were not significantly different between the two groups. Multivariate analysis showed the independent predictors for reduced mid-term survival were the number of total grafts and postoperative periodic renal replacement therapy. Off-pump myocardial revascularization does not decrease the number of bypass grafts or influence on the mid-term results for patients with renal insufficiency, compared to on-pump myocardial revascularization.
CONCLUSION
Myocardial revascularization with a large number of total grafts has a beneficial effect on survival in patients with renal insufficiency, irrespective of utilizing extracorporeal bypass.

Keyword

Myocardial revascularization; Off-pump; On-pump; Kidney failure

MeSH Terms

Extracorporeal Circulation
Humans
Multivariate Analysis
Myocardial Revascularization
Postoperative Period
Renal Insufficiency
Renal Replacement Therapy
Retrospective Studies
Survival Rate
Transplants
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