Lab Anim Res.  2011 Dec;27(4):361-363. 10.5625/lar.2011.27.4.361.

Canine hemangiosarcoma in a female Jindo dog

• Mun A
• Lee EM
• Kim AY
• Lee EJ
• Hong IH
• Jeong KS

• KMID: 1444972
• DOI: http://doi.org/10.5625/lar.2011.27.4.361

Abstract

A fourteen-year female Jindo dog showing signs of hemoperitoneum was diagnosed with hemangiosarcoma through abdominal radiography and histopathological examination. In the abdominal radiographs, a circular mass was observed on the posterior of the spleen. When the splenic mass was removed via laparotomy, it was spherical, poorly circumscribed, and showed signs of necrosis, with white spots present on the outer side of the mass. Microscopically, the mass showed that hemorrhage was widespread and extensive infiltration of neoplastic cells was found throughout. There was hypercellularity, including occasional pleomorphic cells and mitotic figures. Inflammation at the edge of the mass, along with necrosis, was also found. In this report, we describe the gross and histopathological findings of a case of canine hemangiosarcoma.

Keyword

Jindo dog; hemangiosarcoma; spleen

MeSH Terms

Animals
Dental Caries
Dogs
Female
Hemangiosarcoma
Hemoperitoneum
Hemorrhage
Humans
Inflammation
Laparotomy
Necrosis
Radiography, Abdominal
Spleen

Figure

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  Figure 1 Gross findings in the spherical mass. (A) The spherical mass was removed from the spleen. (B) The cut surface shows white spots on the edge, indicating necrosis.

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  Figure 2 Hemorrhage was widespread, making it hard to recognize the normal splenic structure. H&E stain. Scale bar=500 µm.

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  Figure 3 Inflammation and edema were noted with the infiltration of neutrophils and the lack of cell population on the mass edge. H&E stain. Scale bar=50 µm.

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  Figure 4 Multiple cavernous blood channels were formed by tumor cells. Infiltration of tumor cells and tissue reorganization were observed. H&E stain. Scale bar=100 µm.

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  Figure 5 Scattered neoplastic cells and some mitotic figures were evident. H&E stain. Scale bar=50 µm.

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