Clin Pediatr Hematol Oncol.  2012 Apr;19(1):31-39.

Prevalence of Late Effects by Designed Health Promotion Program in Long-term Survivors of Childhood Cancer

Affiliations
  • 1Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea. cord@hanyang.ac.kr
  • 2Department of Psychiatry, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

BACKGROUND
We prospectively investigated the incidence and features of late organ complications in long-term childhood cancer survivors (LTCCS) who took part in a specially designed health promotion program (HPP).
METHODS
We developed our own HPP for LTCCS based on the Children's Oncology Group (COG) program, by modifying the adult HPP in Hanyang University Medical Center. The study included survivors who had received chemotherapy and/or radiotherapy for childhood cancer and had survived for at least 4 years after the end of treatment without evidence of recurrence.
RESULTS
A total of 38 survivors were enrolled in the study. One or more abnormal findings were identified in 33 (87%) of the survivors, and two or more abnormal findings were present in 16 (42%) of the survivors. The most frequent type of abnormality was identified by thyroid ultrasonography, which detected benign nodules or cysts in 17 (45%) of the survivors. High-risk posttraumatic stress disorder needing medical treatment was detected in 1 of 17 survivors who were examined by psychological questionnaire.
CONCLUSION
Most (87%) of childhood cancer survivors have at least 1 major or minor late effect. They must be continuously monitored after completion of treatment for early detection of late effects as well as cancer recurrence. Nationally integrated research is needed to provide standardized and comprehensive HPP for LTCCS considering domestic circumstances in Korea.

Keyword

Long-term survivors; Childhood cancer; Late effects; Health promotion program

MeSH Terms

Academic Medical Centers
Adult
Health Promotion
Humans
Incidence
Korea
Prevalence
Prospective Studies
Recurrence
Stress Disorders, Post-Traumatic
Survivors
Thyroid Gland
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