Korean J Med Mycol.  2013 Mar;18(1):11-15.

Chronic Mucocutaneous Candidiasis Misdiagnosed as Lichen Planus

Affiliations
  • 1Department of Dermatology, College of Medicine, Hallym University, Anyang, Korea. dermakkh@naver.com
  • 2Department of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.

Abstract

Chronic mucocutaneous candidiasis is a rare syndrome characterized by persistent and refractory infection of the skin, nail and mucosal tissue by yeasts of the genus Candida. A 70-year-old woman presented with the following skin lesions: ill-defined annular shaped whitish macules on the upper and lower lips accompanying dryness, pain and burning sensation, and yellowish discoloration with onycholysis of the right 4th finger nail. The upper lip lesion showed histopathologic feature of band-like infiltration of lymphocytes in the upper dermis, consistent with lichen planus. But, systemic glucocorticoid was not effective in treating erosive lip lesions. KOH examination and fungal culture of specimens from the upper lip showed hyphal elements and growth of Candida albicans, respectively. Antifungal agent was administered. After the oral medication, skin lesions were improved but there was repeated recurrence. We report a case of chronic mucocutaneous candidiasis misdiagnosed as lichen planus.

Keyword

Chronic mucocutaneous candidiasis; Lichen planus

MeSH Terms

Burns
Candida
Candida albicans
Candidiasis, Chronic Mucocutaneous
Dermis
Female
Fingers
Humans
Lichen Planus
Lichens
Lip
Lymphocytes
Mucous Membrane
Nails
Onycholysis
Recurrence
Sensation
Skin
Yeasts
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