J Korean Diabetes.  2013 Jun;14(2):83-86. 10.4093/jkd.2013.14.2.83.

Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass

• Ha J
• Park J

• KMID: 1430836
• DOI: http://doi.org/10.4093/jkd.2013.14.2.83

Abstract

Bariatric surgery is one of the most efficient ways to achieve weight loss and reduce the complications associated with obesity. Severe hypoglycemia can occur after bariatric surgery, though it is rare. Hypoglycemic episodes have so far been poorly studied and the pathophysiology of hypoglycemia has not yet been demonstrated. Currently, there are two different hypotheses; the first is that hypoglycemic episodes are secondary to hyperinsulinemia and result from beta-cell hyperplasia or hyperfunction. The second is that the primary problem is beta-cell failure, which allows glucose concentrations to reach high values. The few therapeutic options that have been validated are also discussed in this study.

Keyword

Hypoglycemia; Bariatric surgery; Hyperinsulinism

MeSH Terms

Bariatric Surgery
Gastric Bypass
Glucose
Hyperinsulinism
Hyperplasia
Hypoglycemia
Obesity
Weight Loss
Glucose