Ann Pediatr Endocrinol Metab.
2012 Dec;17(4):249-252. 10.6065/apem.2012.17.4.249.
Proton-Pump Inhibitor-Induced Hypocalcemia and Hypomagnesemia
- Affiliations
-
- 1Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. kimho@yuhs.ac
- KMID: 1429716
- DOI: http://doi.org/10.6065/apem.2012.17.4.249
Abstract
- A 7-day-old female neonate who visited emergency depar tment due to generalized tonic seizure. Laboratory test results showed hypocalcemia (5.7 mg/dL), hypomagnesemia (0.55 mmol/L), low parathyroid hormone (7.5 pg/mL), and normal 25(OH) vitamin D3. Symptom and metabolic abnormalities were normalized with intravenous calcium gluconate and magnesium sulfate. Discharged with supplement of oral calcium, vitamin D, phenobarbital, and lansoprazol, she was re-admitted with hypocalcemia (4.8 mg/dL) with normal level of parathyroid hormone (12.3 pg/mL). Hypocalcemia was resolved with discontinuation of proton pump inhibitor. We report a case of recurrent hypocalcemia and hypomagnesemia due to proton-pump inhibitor.
MeSH Terms
-
2-Pyridinylmethylsulfinylbenzimidazoles
Calcium
Calcium Gluconate
Cholecalciferol
Emergencies
Female
Gluconates
Humans
Hypocalcemia
Hypoparathyroidism
Infant, Newborn
Magnesium Sulfate
Parathyroid Hormone
Phenobarbital
Proton Pumps
Seizures
Vitamin D
2-Pyridinylmethylsulfinylbenzimidazoles
Calcium
Calcium Gluconate
Cholecalciferol
Gluconates
Magnesium Sulfate
Parathyroid Hormone
Phenobarbital
Proton Pumps
Vitamin D
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Is hypomagnesemia associated with using proton pump inhibitors?
- Risk of Pyogenic Liver Abscess in Proton Pump Inhibitor Users: New Inventory of Proton Pump Inhibitor Induced Complications?
- Proton Pump Inhibitor-Responsive Esophageal Eosinophilia: Controversies and Its Clinical Implications
- A Case of Idiopathic Hypomagnesemia with Hypocalcemia Presenting as Generalized Tonic-Clonic Seizure
- Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors
