J Korean Med Sci.  1992 Dec;7(4):385-388. 10.3346/jkms.1992.7.4.385.

A family case of beta-thalassemia minor and hemoglobin Queens: alpha 34 (B15) Leu-Arg

Affiliations
  • 1Department of Clinical Pathology, Seoul National University College of Medicine, Korea.

Abstract

We report a Korean family case of beta-thalassemia minor and Hb Queens. This is the first case report of Hb Queens in Korea. A 43-year-old male and his four family members had beta-thalassemia minor which is very rare in Korea. Incidentally, an alpha chain variant with a high isoelectric point was also found in two other family members without clinical problems and was finally identified as alpha 34 (B15) Leu-Arg or Hemoglobin Queens.

Keyword

beta-thalassemia minor; Hb Queens

MeSH Terms

Adult
Arginine/genetics
Female
Hemoglobins, Abnormal/*genetics
Humans
Korea
Leucine/genetics
Male
Pedigree
beta-Thalassemia/blood/*genetics
Hemoglobins, Abnormal
Leucine
Arginine
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