J Korean Med Sci.  1989 Dec;4(4):179-183. 10.3346/jkms.1989.4.4.179.

So-called sclerosing hemangioma of the lung: two cases report with ultrastructural study

• Park YK
• Yang MH

• KMID: 1421468
• DOI: http://doi.org/10.3346/jkms.1989.4.4.179

Abstract

Sclerosing hemangiomas of the lung are benign neoplasms of uncertain histogenesis. We analysed two cases of sclerosing hemangiomas of the lung with histochemistry and electron microscopy. They had a variegated histologic appearance characterized by an admixture of solid, hemorrhagic, papillary and sclerotic lesions. Characteristic uniform round cells, unique to this tumor, were found within the stroma in all lesions. In the electron microscopic examination, we found Weibel-Palade bodies like small bodies in the tumor cells. We suspect hypothesis originating in the endothelial cell can not be completely excluded yet. Sclerosing hemangioma is a distinct clinicopathologic entity and should be distinguished from other benign neoplasms or inflammatory lesions of the lung.

Keyword

Sclerosing hemangioma; lung; Weibel-Palade body; endothelial cell

MeSH Terms

Endothelium/ultrastructure
Female
Histiocytoma, Benign Fibrous/pathology/*ultrastructure
Humans
Lung Neoplasms/pathology/*ultrastructure
Male
Middle Aged