J Korean Med Sci.
1989 Sep;4(3):149-153. 10.3346/jkms.1989.4.3.149.
Clear cell sarcoma of the kidney: a case report
- Affiliations
-
- 1Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.
- KMID: 1421463
- DOI: http://doi.org/10.3346/jkms.1989.4.3.149
Abstract
- Clear cell sarcoma of the kidney (CCSK) is a highly malignant childhood tumor, distinguished from classic Wilms' tumor by its propensity to metastasize to the skeletal system. Authors described a case of CCSK from a 3-year-old boy in the right kidney, showing various histologic features, such as classic, epithelioid, trabecular, neurilemmoma-like, cystic and entrapped collecting tubular pattern. Ultrastructurally epithelial differentiation was absent. Immunohistochemically, none of the intrinsic tumor cells showed positive staining with the antibodies against the keratin, S-100 protein, carcinoembryonic antigen, vimentin, desmin and myoglobin, suggesting primitive mesenchymal cell in origin.
