J Korean Med Sci.  1989 Jun;4(2):103-109. 10.3346/jkms.1989.4.2.103.

Acquired immune deficiency syndrome: report of an autopsy case

• Lee GK
• Lee YS
• Park SH
• Chi JG
• Kim YI
• Choe KW

• KMID: 1421455
• DOI: http://doi.org/10.3346/jkms.1989.4.2.103

Abstract

Authors report the first autopsy case of acquired immune deficiency syndrome in Korea. The patient was a 26 years old Korean male who died of respiratory failure due to mixed pulmonary infections. He had history of homosexual contacts with partners of both domestic and foreign nationalities. Initial presentation was unexplained fever for two months. Serological test and western blot test for anti-HIV were positive and T-cell subset analysis revealed T3/T4/T8 to be 73/8/67%. Pulmonary tuberculosis with mediastinal lymphadenopathy and esophagonadal fistula and oral candidiasis were presented. Respiratory infection progressed gradually and he died seven months after the initial symptom. Autopsy findings were generalized severe lymphoid cell depletion, especially of T-cell population and mixed pulmonary infections with Pneumocystis carinii and cytomegalovirus (CMV). The CMV infection involved lungs and adrenals. Oral candidiasis was also demonstrated.

Keyword

Acquired immune deficiency syndrome (AIDS); Pathology; Pneumocystis carinii pneumonia; Cytomegalovirus

MeSH Terms

AIDS-Related Complex/complications/diagnosis/pathology
Acquired Immunodeficiency Syndrome/complications/*diagnosis/pathology
Adult
Autopsy
Candidiasis/complications/diagnosis/pathology
Humans
Male
Pneumonia, Pneumocystis/complications/diagnosis/pathology
Tuberculosis, Pulmonary/complications/diagnosis/pathology