J Vet Sci.  2012 Jun;13(2):207-209. 10.4142/jvs.2012.13.2.207.

Sertoli cell tumors associated with feminizing syndrome and spermatic cord torsion in two cryptorchid dogs

• Quartuccio M
• Marino G
• Garufi G
• Cristarella S
• Zanghi A

• KMID: 1376197
• DOI: http://doi.org/10.4142/jvs.2012.13.2.207

Abstract

The association of cryptorchidism, functional Sertoli cell tumors, and spermatic cord torsion has been rarely reported in the literature. Two dogs were admitted for bilateral skin alopecia and weight loss. Both animals were cryptorchid and displayed a pendulous preputial sheath, prostate hypertrophy, and increased levels of circulating oestrogen. Transabdominal palpation and ultrasonography revealed the presence of neoplastic retained gonads. During surgery, spermatic cord torsion was also detected in the enlarged neoplastic testes of both dogs. Histologic examination confirmed the presence of Sertoli cell tumors that were primarily responsible for the feminizing syndrome. Complete remission of all symptoms occurred within 3 months after orchiectomy.

Keyword

cryptorchidism; dog; feminizing syndrome; Sertoli cell tumor; spermatic cord torsion

MeSH Terms

Animals
Cryptorchidism/pathology/surgery/*veterinary
Dog Diseases/*pathology/surgery
Dogs
Male
Sertoli Cell Tumor/pathology/surgery/*veterinary
Spermatic Cord Torsion/pathology/surgery/*veterinary
Treatment Outcome

Figure

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  Fig. 1 Case 1. (A) A dog presenting characteristic bilateral symmetrical alopecia with hyperkeratosis involving the ventral abdomen, flanks, thorax, and neck. (B) The left testis at surgery was greatly increased in size and had multiple spermatic cord torsions (arrow).

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  Fig. 2 Case 2. Gross appearance of a totally neoplastic testis compared to the contralateral atrophic one.

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  Fig. 3 Case 2. Epithelial cells with signs of squamous metaplasia collected from a prostatic cyst. May-Grünwald-Giemsa stain, ×250.

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