Korean J Urol.  2008 Nov;49(11):1051-1054. 10.4111/kju.2008.49.11.1051.

Myxofibrosarcoma of Bladder

• Lee SR
• Choi J
• Jeon BJ
• Yang KS
• Kim IG
• Lee JO
• Han BH

• KMID: 1328181
• DOI: http://doi.org/10.4111/kju.2008.49.11.1051

Abstract

Myxofibrosarcoma is also known as a myxoid variant of malignant fibrous histiocytoma, and this is one of the most common sarcomas in the extremities of elderly people; it is characterized by a high frequency of local recurrence. We herein report on a case of myxofibrosarcoma of the bladder. A 58-year-old man was referred to our hospital because of microscopic hematuria. Computed tomography(CT) and intravenous pyelography(IVP) showed a 12x7cm sized bladder mass in the pelvic cavity. The cystoscopic finding shows a protruding mass at the dome and posterior wall of the bladder. After exploratory laparotomy and tissue frozen biopsy were done, radical cystectomy and uretero-ileo-cutaneous anastomosis were then carried out. The diagnosis of the tumor was confirmed by histopathological examination. The myxofibrosarcoma of the bladder was completely excised, and there was no evidence of recurrence after 10 months of follow-up.

Keyword

Myxofibrosarcoma; Bladder

MeSH Terms

Male
Humans
Biopsy

Figure

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  Fig. 1. The computed tomography (CT) scan and intravenous pyelography (IVP) reveal a huge solid mass that is located at the bladder. (A) Pre-contrast enhanced CT scan, (B) Post-contrast enhanced CT scan, (C) Coronary section of the post-contrast enhanced CT scan, (D) IVP, 25 mins view.

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  Fig. 2. The cystoscopic finding shows a protruding mass at the dome (A) and posterior wall (B) of the bladder.

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  Fig. 3. Gross and microscopic findings. (A) A irregular bosselated mass is attached to the bladder mucosa. (B) Prominent elongated & thin walled blood vessels with tumor cells (H&E, x40). (C) Alternation of cellular and myxoid areas (H&E, x100). (D) Frequent bizarre multinucleated giant cells with abundant eosinophilic cytoplasm and irregular shaped nuclei (H&E, x200).

Reference

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