Korean J Ophthalmol.  1999 Dec;13(2):133-37. 10.3341/kjo.1999.13.2.133.

Phakomatous choristoma of the eyelid

• Shin HM
• Song HG
• Choi MY

• KMID: 1127517
• DOI: http://doi.org/10.3341/kjo.1999.13.2.133

Abstract

This article describes the first report of phakomatous choristoma of the eyelid in Korea. A six-month-old boy underwent excision of a congenital inferonasal orbital mass arising from the left lower lid. A dermoid cyst was suspected, however a diagnosis of phakomatous choristoma was made following conventional histology. An immunohistochemical study of this rare benign congenital tumor was conducted. The cuboidal epithelial cells comprising this choristoma showed strongly positive cytoplasmic staining with S-100 protein and vimentin. They also showed focally positive staining with a neuron-specific enolase, while they showed no immunoreactivity to cytokeratin or epithelial membrane antigen. The results of the immunohistochemical study support the conclusion that this tumor is of lenticular anlage origin.

MeSH Terms

Biological Markers
CA-15-3 Antigen/metabolism
Case Report
Choristoma/metabolism
Choristoma/diagnosis*
Diagnosis, Differential
Epithelial Cells/pathology
Eyelid Diseases/metabolism
Eyelid Diseases/diagnosis*
Human
Infant
Keratin/metabolism
Lens, Crystalline*
Male
Nerve Tissue Protein S 100/metabolism
Phosphopyruvate Hydratase/metabolism
Tomography, X-Ray Computed
Vimentin/metabolism