Yonsei Med J.  1991 Mar;32(1):53-57. 10.3349/ymj.1991.32.1.53.

Neurosurgical application of fibrin adhesive

• Lee KC
• Park SK
• Lee KS

• KMID: 1117736
• DOI: http://doi.org/10.3349/ymj.1991.32.1.53

Abstract

We have tried fibrin adhesive, which mimics the end stage of plasmatic coagulation, in 26 patients with various neurosurgical problems such as: repair of cerebrospinal fluid (CSF) leaks, sealing of the vascular anastomosis sites, reinforcements of aneurysmal clippings, and hemostasis after resection of brain tumors. Presented in this report are 11 intracranial aneurysms, 11 brain tumors, 2 lipomyelo-meningoceles, and one each of cerebral arteriovenous malformation and torn dura resulting from a mastoidectomy. Procedures which seemed to be impossible or very difficult by conventional neurosurgical techniques could be accomplished in all cases without any complication. Our experience with fibrin adhesive suggests that it is a valuable adjuvant to various microneurosurgical procedures, and it may be potentially useful for protection of major cerebral veins and venous sinuses during cerebral retraction.

Keyword

Fibrin adhesive; biological glue; reinforcement; reconstruction

MeSH Terms

Adolescent
Adult
Aneurysm/surgery
Child, Preschool
Female
Fibrin Tissue Adhesive/*pharmacology
Hemostatic Techniques
Human
Male
Middle Aged
Neurosurgery