Yonsei Med J.  1990 Sep;31(3):212-218. 10.3349/ymj.1990.31.3.212.

Histopathological and immunohistochemical studies of polymorphic reticulosis

• Park YN
• Yang WI
• Lee KG
• Choi IJ

• KMID: 1107338
• DOI: http://doi.org/10.3349/ymj.1990.31.3.212

Abstract

This study reviewed 65 cases of polymorphic reticulosis (PR) with respect to clinical and histopathologic bases, and immunohistochemical studies were done using MT1 and UCHL as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic marker. The results obtained were as follows: 1. The male to female ratio was 2.4:1 and the mean age of patients was 44.5 years. The sites involved primarily were the nasal cavity, tonsil and pharynx and about one-fourth of the total cases showed extensive involvement of two anatomical sites at initial presentation. 2. Almost all cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reaction to the T-cell marker. The above immunohistochemical findings suggest strongly that quite a significant portion of PR is in fact T-cell lymphoma.

Keyword

Lethal midline granuloma; polymorphic reticulosis; peripheral T-cell lymphoma

MeSH Terms

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, Differentiation, T-Lymphocyte/*analysis
Antigens, Neoplasm/analysis
Blood Sedimentation
Comparative Study
Female
Head and Neck Neoplasms/chemistry/*pathology
Human
Lymphoma, T-Cell/*pathology
Male
Middle Age
Nasopharyngeal Neoplasms/chemistry/pathology
Neoplasm Proteins/analysis
Reticuloendotheliosis/metabolism/*pathology
Support, Non-U.S. Gov't
Tumor Markers, Biological/analysis