Yonsei Med J.  1990 Sep;31(3):205-211. 10.3349/ymj.1990.31.3.205.

A clinicopathological study of Kimura's disease and epithelioid hemangioma

Affiliations
  • 1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

The clinicopathological features of 9 cases of Kimura's disease and 5 cases of epithelioid hemangioma(EH) were reviewed. Patients with Kimura's disease presented with multiple or solitary large tumors occurring in the thigh, arms as well as parotid gland. Histologically, the lesions were characterized by numerous lymphoid follicles with proliferation of post-capillary venules lined by plump endothelium and a marked eosinophilic infiltration. Patients with EH were older than those with Kimura's disease and presented papular nodular lesions, less than 1 cm in size. Microscopically, there was proliferation of blood vessels lined by epithelioid endothelium with infiltration by lymphocytes and eosinophils. Although there may occasionally be clinicopathological overlap between Kimura's disease and EH, we consider that these two disorders can be recognized as separate entities.

Keyword

Kimura's disease; epithelioid hemangioma; angiolymphoid hyperplasia with eosinophilia

MeSH Terms

Adult
Angiolymphoid Hyperplasia with Eosinophilia/*pathology
Comparative Study
Female
Head and Neck Neoplasms/pathology
Hemangioma/*pathology
Human
Male
Middle Age
Neoplasms, Multiple Primary/*pathology
Skin Neoplasms/*pathology
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