Yonsei Med J.  2002 Jun;43(3):377-380. 10.3349/ymj.2002.43.3.377.

An Unusual Case of Osteoblastic Metastasis from Gastric Carcinoma

Affiliations
  • 1Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea. yschung@madang.ajou.ac.kr
  • 2Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea.
  • 3Department of Nuclear Medicine, Ajou University School of Medicine, Suwon, Korea.
  • 4Division of Endocrinology, Metabolism and Nutrition, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.

Abstract

We report an unusual case of osteoblastic metastasis from gastric carcinoma. In this case, bone metastasis was the initial manifestation of the cancer. The laboratory findings revealed mild hypocalcemia and markedly elevated alkaline phosphatase levels. Plain X-ray showed mottled osteoblastic changes in the pelvis. Bone marrow and bone biopsy of the pelvis revealed metastatic adenocarcinoma with increased osteoblastic activity. An extensive search for the primary site revealed advanced gastric carcinoma, which was confirmed by endoscopic biopsy.

Keyword

Osteoblastic metastasis; gastric carcinoma

MeSH Terms

Adenocarcinoma/diagnosis/*secondary
Adult
Bone Neoplasms/*diagnosis/pathology/*secondary
Case Report
Female
Human
*Osteoblasts/radiography
*Pelvis/radiography
Radionuclide Imaging
Stomach Neoplasms/*diagnosis
Tomography, X-Ray Computed

Cited by  1 articles

Bone Metastasis in Gastric Cancer Patients
Jae Bong Ahn, Tae Kyung Ha, Sung Joon Kwon
J Gastric Cancer. 2011;11(1):38-45.    doi: 10.5230/jgc.2011.11.1.38.

Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr