J Vet Sci.  2001 Aug;2(2):143-145.

Lymphosarcoma in a brown bear (Ursus arctos)

• Yoon BI
• Lee JK
• Kim JH
• Shin NS
• Kwon SW
• Lee GH
• Kim DY

Abstract

An example of lymphoblastic lymphosarcoma was found in a 7-year-old male brown bear (Ursus arctos) that died after having a 7-month history of depression, anorexia and watery diarrhea. Grossly the mesenteric lymph nodes were enlarged to approximately 4 to 6 times their normal size and histologically diagnosed as lymphoblastic lymphosarcoma. The small intestinal mucosa was corrugated and had severe mural thickening due to infiltrated neoplastic cells. Hepatic metastasis was also noted. This is the first reported case of lymphosarcoma in Ursidae in Korea. As an incidental finding, endogenous lipid pneumonia was noted in the lung.

Keyword

Lymphosarcoma; bear; Ursidae; endogenous lipid pneumonia

MeSH Terms

Animals
Animals, Zoo
Fatal Outcome
Intestinal Mucosa/pathology
Intestine, Small/pathology
Korea
Liver/pathology
Liver Neoplasms/secondary/veterinary
Lung/pathology
Lymph Nodes/*pathology
Male
Mesentery
Pneumonia, Lipid/pathology/veterinary
Precursor Cell Lymphoblastic Leukemia-Lymphoma/diagnosis/pathology/*veterinary
*Ursidae