Korean J Radiol.  2008 Jul;9(Suppl):S43-S47. 10.3348/kjr.2008.9.s.s43.

Carney Complex with Multiple Intracranial Aneurysms

• Gwak YJ
• Kim HJ
• Baik SK
• Kang DS

• KMID: 1100103
• DOI: http://doi.org/10.3348/kjr.2008.9.s.s43

Abstract

Carney complex is an autosomal dominant disease that displays such characteristic features as cardiac and cutaneous myxomas and spotty pigmentation of the skin. We report here on a case of Carney complex that was accompanied by increased myxoid fibroadenomas in the breast and multiple intracranial aneurysms.

Keyword

Myxoma; Aneurysm, intracranial; Breast neoplasms, diagnosis

MeSH Terms

Adult
Breast Neoplasms/*complications/diagnosis
Female
Fibroadenoma/*complications/diagnosis
Humans
Intracranial Aneurysm/*complications
Magnetic Resonance Imaging
Pigmentation Disorders/*complications
Syndrome

Figure

• 

  Fig. 1 Carney complex associated with breast myxoid fibroadenomas and intracranial aneurysms in 37-year-old woman. A. Mediolateral oblique mammogram of right breast shows multiple nodules (arrows). B. Ultrasonogram of right breast shows hypoechoic well-defined nodule (arrowhead). C. Follow-up ultrasonogram of right breast reveals increased hypoechoic or isoechoic well-defined nodules (arrows) as compared with previous one (arrowhead in B). D. Photomicrograph (original magnification,×40; Hematoxylin & Eosin staining) of pathologic specimen of breast demonstrates proliferated myxoid stroma. E. Photomicrograph (original magnification,×100; Hematoxylin & Eosin staining) of pathologic specimen of forearm shows abundant myxoid matrix. F. T2-weighted MR image of breast reveals multiple well-defined ovoid nodules (arrows) with bright signal intensity. G. T1-weighted dynamic subtraction MR images show persistent enhancement in lesion (arrows). H. Two foci were selected as regions of interest. Signal-to-time curve indicates persistent enhancement in lesions. I, J. Anteroposterior (I) and lateral (J) left vertebral angiogram depicts multiple fusiform dilatations in basilar artery (black arrowhead), left posterior cerebral artery (P2 segment) (black arrow) and right posterior cerebral artery (P4 segment) (white arrow). K. Oblique left internal carotid angiogram shows aneurysm of temporal branch of left middle cerebral artery (white arrowhead). L. Oblique right internal carotid angiogram shows aneurysms of distal branches of right middle cerebral artery (short black arrow) and right anterior cerebral artery (short white arrow).

Reference

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