J Vet Sci.  2004 Sep;5(3):267-270.

Use of the n-butyl cyanoacrylate adhesive and the polyglactine thread suture for corneal rhaphy in rabbit (Oryctolagus cunicullus)

Affiliations
  • 1College of Veterinary Medicine, Federal University of Uberlandia, Minas Gerais, Brasil. dantasmota@yahoo.com.br
  • 2College of Veterinary Medicine, Federal University of Goiania, Goias, Brasil.

Abstract

The aim of this study was to evaluate the cicatricial repair of perforating cornea in rabbits, by using the Nbutyl cyanoacrylate adhesive compared to the 910-polyglactine thread suture through macroscopic and histological assays. Corneas from 18 adult rabbits were perforated and subsequently occluded with N-butyl cyanoacrylate synthetic adhesive (right cornea) or by separated single points using the 910-polyglactine thread (left cornea). The rabbits were divided into groups containing three animals per group. Examination after 7, 15, and 30 days post-operative showed that both the synthetic adhesive and the suture were efficient in the occlusion of the surgical wounds, thus stabilizing the intra-ocular content. The N-butyl cyanoacrylate adhesive was shown to be superior to the 910-polyglactine suture thread with regards to the evolution and the organization of the healing process.

Keyword

rabbit; cornea; surgery; suture; synthetic adhesive

MeSH Terms

Animals
Cornea/*injuries/*surgery
Enbucrilate/*therapeutic use
Female
Male
Polyglactin 910/therapeutic use
Rabbits/*surgery
*Sutures
Tissue Adhesives/*therapeutic use
*Wound Healing
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