Korean J Ophthalmol.  2007 Sep;21(3):169-171. 10.3341/kjo.2007.21.3.169.

A Solitary Fibrofolliculoma in the Eyelid

  • 1Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea. cataract@empal.com


PURPOSE: To report the first case of a solitary eyelid fibrofolliculoma and to review the literature. METHODS: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year. The patient had visited the local clinic, and under the diagnosis of chalazion had received incision and curettage twice, but the lesion had recurred. RESULTS: The 5 x 5 mm lesion was located near the upper lid margin. It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful. Excision and biopsy were performed, and through a histological exam, the diagnosis of fibrofolliculoma was later confirmed. CONCLUSIONS: Solitary fibrofolliculoma is rare, and to the authors' knowledge, a lesion arising in the eyelid has not yet been reported. Fibrofolliculoma should be included in the differential diagnosis when a localized mass lesion arising in the eyelid is encountered.


Eyelid neoplasm; Solitary fibrofolliculoma

MeSH Terms

Diagnosis, Differential
Eyelid Neoplasms/*diagnosis/pathology/surgery
Ophthalmologic Surgical Procedures


  • Fig. 1 (A) Preoperative appearance shows a solitary, firm, non-tender, well-demarcated and skin-colored bean-sized mass on the right upper eyelid. (B) Postoperative (11 months) appearance shows the right upper lid, which has maintained its shape; the lesion has not yet recurred.

  • Fig. 2 Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).

  • Fig. 3 High-power histopathologic photograph showing the characteristic appearances of proliferating infundibular epithelial strands with perifollicular fibrous reaction, anastomosing to form an epithelial network (arrow: hair follicle, Hematoxylin-eosin stain, ×100).


1. Birt AR, Hogg GR, Dubé WJ. Hereditary multiple fibrofolliculomas with trichodiscomas and acrochordons. Arch Dermatol. 1977. 113:1674–1677.
2. Weintraub R, Pinkus H. Multiple fibrofolliculomas (Birt-Hogg-Dubé) associated with a large connective tissue nevus. J Cutan Pathol. 1977. 4:289–299.
3. Scully K, Bargman H, Assaad D. Solitary fibrofolliculoma. J Am Acad Dermatol. 1984. 11:361–363.
4. Fujita WH, Barr RJ, Headley JL. Multiple fibrofolliculomas with trichodiscomas and acrochordons. Arch Dermatol. 1981. 117:32–35.
5. Pinkus H, Coskey R, Burgess GH. Trichodiscoma. A benign tumor related to haarscheibe (hair disk). J Invest Dermatol. 1974. 63:212–218.
6. Starink TM, Brownstein MH. Fibrofolliculoma: solitary and multiple types. J Am Acad Dermatol. 1987. 17:493–496.
7. Foucar K, Rosen T, Foucar E, et al. Fibrofolliculoma: a clinicopathologic study. Cutis. 1981. 28:429–432.
8. Rahbari H, Mehregan AH. Benign follicular neoplasias. J Dermatol Surg Oncol. 1979. 5:295–298.
9. Starink TM, Kisch LS, Meijer CJ. Familial multiple trichodiscomas. A clinicopathologic study. Arch Dermatol. 1985. 121:888–891.
10. Mo HJ, Park CJ, Yi JY. A Case of Solitary Fibrofolliculoma. Korean J Dermatol. 2001. 39:602–604.
11. Kim KH, Choi JH, Lee YS. A Case of Solitary Fibrofolliculoma. Korean J Dermatol. 1984. 22:672–674.
12. Lee HK, Maeng LS, Kang SJ, et al. Solitary fibrofolliculoma: A case report. Kor J Pathol. 1996. 30:460–462.
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