J Korean Med Sci.  2005 Apr;20(2):232-235. 10.3346/jkms.2005.20.2.232.

Effects of Preoperative Anxiety on Gastric Fluid Acidity and Volume

Affiliations
  • 1Department of Anesthesiology, Samsung Cheil Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea. jenyhongg@hanmail.net

Abstract

The aim of this study was to evaluate the effect of preoperative anxiety on the gastric pH and volume. We studied 96 female patients aged 16-60 yr who underwent elective gynecological surgery. We classified the subjects into 2 groups, those presenting preoperative anxiety scores using visual analogue scale (VAS, 0-10) less than 5 (L-group, n=59), and those with 5 and more (H-group, n=37). Immediately after tracheal intubation, gastric contents were aspirated using a 14-F multiorifice nasogastric tube. The gastric acidity and volume of the two groups were not statistically different. Mean pH were 3.0+/-1.8 and 3.0+/-2.0 in each group (L-group and H-group) and mean gastric volume (mL) were 15.3 +/-11.7 and 11.8 +/-11.8, respectively. Nine (15.3%) patients in the L-group were considered to be 'at risk i.e. gastric pH <2.5 and volume >25 mL' and one patient (2.7%) in the H-group (p<0.05). The mean serum gastrin concentrations in both groups were similar (21.6+/-9.8 vs. 20.2+/-11.0 pg/mL). The pH and volume of preoperative gastric contents were not correlated with the preoperative anxiety. The results suggest that a low level of preoperative anxiety can be considered a risk factor for aspiration pneumonitis.

Keyword

Preoperative Care; Anxiety; Gastric Acid

MeSH Terms

Adolescent
Adult
Anxiety/*metabolism
Female
*Gastric Acidity Determination
Gastric Juice/metabolism
Humans
Middle Aged

Figure

  • Fig. 1 Gastric pH and volume of gynecologic patients in low anxiety group (L-group, n=59) and high anxiety group (H-group, n=37). There were 9 (15.2%) patients considered to be 'at risk: pH <2.5 and volume >25 mL' in the L-group, and 1 (2.7%) in the H-group (p<0.05). Lines are drawn at pH=2.5 and volume=25 mL.

  • Fig. 2 Relationship between preoperative anxiety and gastric fluid. The pH (A) and volume (B) of preoperative gastric contents were not significantly associated with preoperative anxiety.


Reference

1. Olsson GL, Hallen B, Hambraeus-Jonzon K. Aspiration during anaesthesia: a computer-aided study of 185,358 anaesthetics. Acta Anaesthesiol Scand. 1986. 30:84–92.
2. Ong BY, Palahniuk RJ, Cumming M. Gastric volume and pH in outpatients. Can Anaesth Soc J. 1978. 25:36–39.
Article
3. Cote CJ, Goudsouzian NG, Liu LM, Dedrick DF, Szyfelbein SK. Assessment of risk factors related to the acid aspiration syndrome in pediatric patients: gastric pH and residual volume. Anesthesiology. 1982. 56:70–72.
4. Nygren J, Thorell A, Jacobsson H, Larsson S, Schnell PO, Hylen L, Ljunggvist O. Preoperative gastric emptying: effects of anxiety and oral carbohydrate administration. Ann Surg. 1995. 222:728–734.
Article
5. Lydon A, McGinley J, Cooke T, Duggan PF, Shorten GD. Effect of anxiety on the rate of gastric emptying of liquids. Br J Anaesth. 1998. 81:522–525.
Article
6. Haavik PE, Soreide E, Hofstad B, Steen PA. Does preoperative anxiety influence gastric fluid volume and acidity? Anesth Analg. 1992. 75:91–94.
Article
7. Lindstedt G, Olbe L, Kilander AF, Armbrecht U, Jagenburg R, Runsteen D, Lundberg PA. Analytical and clinical evaluation of a radioimmunoassay for gastrin. Clin Chem. 1985. 31:76–82.
Article
8. Simpson KH, Stakes AF. Effect of anxiety on gastric emptying in preoperative patients. Br J Anaesth. 1987. 59:540–544.
Article
9. Kawana S, Uzuki M, Nakae Y, Namiki A. Preoperative anxiety and volume and acidity of gastric fluid in children. Paediatr Anaesth. 2000. 10:17–21.
Article
10. Rees MR, Barber D, Clark RA, Holdsworth CD, Howlett PJ. Effect of beta adrenergic drugs and beta blocking agents on gastric emptying in man. Gut. 1978. 19:A435.
11. Clark RA, Holdsworth CD, Rees MR, Howlett PJ. The effect on paracetamol absorption of stimulation and blockade of beta-adrenoceptors. Br J Clin Pharmacol. 1980. 10:555–559.
Article
12. Christensen KC, Stadil F. Effect of epinephrine and norepinephrine on gastrin release and gastric secretion of acid in man. Scand J Gastroenterol (Suppl). 1976. 37:87–92.
13. Gill RC, Murphy PD, Hooper HR, Bowes KL, Kingma YJ. Effect of the menstrual cycle on gastric emptying. Digestion. 1987. 36:168–174.
Article
14. Goo RH, Moore JG, Greenberg E, Alazraki NP. Circadian variations in gastric emptying of meals in humans. Gastroenterology. 1987. 93:515–518.
15. Taylor WJ, Champion MC, Barry AW, Hurtig JB. Measuring gastric contents during general anaesthesia: evaluation of blind gastric aspiration. Can J Anaesth. 1989. 36:51–54.
Article
16. Kindler CH, Harms C, Amsler F, Ihde-Scholl T, Scheidegger D. The visual analog scale allows effective measurement of preoperative anxiety and detection of patients' anesthetic concerns. Anesth Analg. 2000. 90:706–712.
Article
Full Text Links
  • JKMS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr