Korean J Radiol.  2009 Oct;10(5):511-514. 10.3348/kjr.2009.10.5.511.

Hypereosinophilia with Multiple Thromboembolic Cerebral Infarcts and Focal Intracerebral Hemorrhage

• Lee EJ
• Lee YJ
• Lee SR
• Park DW
• Kim HY

• KMID: 1093967
• DOI: http://doi.org/10.3348/kjr.2009.10.5.511

Abstract

We report a case of hypereosinophilia causing multiple areas of cerebral infarcts. A 52-year-old Korean man presented with dysarthria and weakness in both arms. A brain MRI revealed multiple acute infarcts in the distal border zone with focal intracerebral hemorrhage, whereas a cerebral angiogram was not remarkable. The eosinophil count was 5,500/microLiter and was accompanied by elevated cardiac enzyme levels. The pattern of cerebral infarcts and laboratory results suggest a thromboembolic infarction associated with hypereosinophilia.

Keyword

Hypereosinophilic syndrome; Infarction, cerebral; Thromboembolism; Intracerebral hemorrhage

MeSH Terms

Cerebral Hemorrhage/diagnosis/*etiology
Cerebral Infarction/diagnosis/*etiology
Diagnosis, Differential
Eosinophilia/*complications/drug therapy
Humans
Magnetic Resonance Imaging
Male
Middle Aged

Figure

• 

  Fig. 1 Hypereosinophilia with multiple thromboembolic cerebral infarcts and focal intracerebral hemorrhaging in 52-year-old man. A-C. Diffusion-weighted image (A) reveals multiple acute infarcts in bilateral border zones. T2-weighted image (B) and gradient echo image (C) reveal focal intracerebral hemorrhaging (arrows) at left frontal white matter. D. Axial high resolution CT scan of lung reveals multiple nodules (arrows). E-H. Cerebral MR angiography (E) and digital subtraction angiography (F-H) shows no evidence of arterial or venous sinus abnormalities.

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