J Vet Sci.  2004 Dec;5(4):359-367.

Effect of probiotic containing Saccharomyces boulardii on experimental ochratoxicosis in broilers: hematobiochemical studies

• Agawane SB
• Lonkar PS

Abstract

In the present investigation, the toxicopathological effects of ochratoxin A of 0.5 ppm on hematobiochemical parameters of broilers were studied with efficacy of dietary concentration of probiotic containing yeast culture Saccharomyces boulardii of 10 mg/kg of feed. One hundred twenty day old chicks were randomly divided into four groups, thirty chicks each. Groups A and C chicks were offered normal feed and that added with probiotic Saccharomyces boulardii respectively. The birds in group B were fed ochratoxin A of 0.5 ppm of feed. Where as, the birds of group D, were fed with ochratoxin A of 0.5 ppm along with probiotic Saccharomyces boulardii of 10 mg/kg of diet. Hematological studies carried revealed significant decrease in the haemoglobin and packed cell volume in birds of group B and reduced effect in birds of group D due to probiotic. Biochemical profiles revealed significant improvement in probiotic treated group D when compared with decreased values of Total protein, albumin, globulin and increased levels of serum creatinine and SGPT in birds of groups B.

Keyword

Saccharomyces boulardii; ochratoxin A; hematological; biochemical

MeSH Terms

Alanine Transaminase/blood
Animal Feed
Animals
Carcinogens/*toxicity
Chickens/blood
Creatinine/blood
Hematocrit/veterinary
Mycotoxicosis/blood/prevention&control/*veterinary
Ochratoxins/*toxicity
Poultry Diseases/blood/*prevention&control
Probiotics/*therapeutic use
Saccharomyces/*physiology