Yonsei Med J.  2008 Apr;49(2):244-248. 10.3349/ymj.2008.49.2.244.

Surgical Treatment Using an Allograft Dermal Matrix for Nasal Septal Perforation

• Lee KC
• Lee NH
• Ban JH
• Jin SM

• KMID: 1084497
• DOI: http://doi.org/10.3349/ymj.2008.49.2.244

Abstract

PURPOSE
Numerous methods have been utilized to repair nasal septal perforation with varying degrees of success; however, no consensus has been reached on nasoseptal perforation repair. Here, the authors describe a surgical method based on human dermal allograft (Surederm(TM), Hans Biomed Corp. Korea) for the repair of nasal septal perforations. MATERIALS AND METHODS: Eleven patients with a nasal septal perforation were included in this study. The causes of these septal perforations included previous nasal surgery, trauma, foreign body (button battery), and idiopathy. There were several sites of perforation: 9 in the central area, 1 in the posterior-central area, and 1 in the anterior area. An interpositional graft incorporating Surederm(TM) was positioned between bilateral mucoperichondrial flaps using an intranasal approach. A silastic sheet was then left in the nasal septum bilaterally until complete healing had occurred through new nasal mucosa, which took a mean duration of 6 weeks. RESULTS: Outcomes in ten of the eleven patients were successful, with complete septal perforation closure. The remaining perforation, which was caused by a button battery, closed incompletely; however, its initial size of 2cm was reduced to 5mm. CONCLUSION: The described technique has a high success rate and can be performed under local anesthesia without external scarring. In the absence of donor site morbidity, this technique can also be utilized to repair posterior or multiple septal perforations without difficulty.

Keyword

Allograft; nasal septum

MeSH Terms

Adolescent
Adult
Aged
Child
Dermis/*transplantation
Female
Humans
Male
Middle Aged
Nasal Septum/pathology/*surgery
Nose Diseases/*surgery
Skin Transplantation/methods
Transplantation, Homologous
Treatment Outcome

Figure

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  Fig. 1 Schematic figure of the surgical technique.

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  Fig. 2 Preoperative view of septal perforation (A). A silastic sheet was inserted into both nasal cavities to protect Surederm (B). Postoperative view showing good healing of the perforated septum (C).

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